1 00:00:00,440 --> 00:00:06,472 ANTHONY: The history of 5.301, right here. 2 00:00:06,472 --> 00:00:42,750 [MUSIC PLAYING] 3 00:00:42,750 --> 00:00:44,070 IKE: It's over. 4 00:00:44,070 --> 00:00:46,040 And I miss it already. 5 00:00:46,040 --> 00:00:49,800 NARRATOR: It's the last day of 5.301. 6 00:00:49,800 --> 00:00:52,520 Next week, everybody will turn in their lab reports. 7 00:00:52,520 --> 00:00:55,850 And the week after that, they'll all pass the class. 8 00:00:55,850 --> 00:00:57,495 IKE: I came with no lab experience. 9 00:00:57,495 --> 00:00:59,660 This is my first ever lab. 10 00:00:59,660 --> 00:01:02,110 ETHAN: I didn't have any research experience coming 11 00:01:02,110 --> 00:01:04,190 here at MIT, at least in the sciences. 12 00:01:04,190 --> 00:01:06,360 LINA: In the beginning, I understood nothing. 13 00:01:06,360 --> 00:01:07,290 IKE: I learned a lot. 14 00:01:07,290 --> 00:01:10,240 I actually knew the whole theoretical part of it. 15 00:01:10,240 --> 00:01:13,420 But I was always interested in getting to know this part too. 16 00:01:13,420 --> 00:01:16,770 LEALIA: And I learned a lot about chem lab techniques. 17 00:01:16,770 --> 00:01:18,950 IKE: I got a hang of it. 18 00:01:18,950 --> 00:01:20,260 Starting, I was really bad. 19 00:01:20,260 --> 00:01:22,550 You could asK Phil or anyone. 20 00:01:22,550 --> 00:01:25,310 LINA: As I've progressed in this class, I think I've 21 00:01:25,310 --> 00:01:27,960 gotten a lot better. 22 00:01:27,960 --> 00:01:30,090 NARRATOR: It's been a journey for everyone. 23 00:01:30,090 --> 00:01:32,140 But it's not all about the science. 24 00:01:32,140 --> 00:01:34,160 LINA: The best thing about 5.301 was 25 00:01:34,160 --> 00:01:35,430 getting to meet the people. 26 00:01:35,430 --> 00:01:37,390 It was really, really fun. 27 00:01:37,390 --> 00:01:38,590 ETHAN: It was a lot of fun. 28 00:01:38,590 --> 00:01:40,660 DAN: I had a ton of fun in lab, meeting 29 00:01:40,660 --> 00:01:42,300 everyone, making friends. 30 00:01:42,300 --> 00:01:44,560 ETHAN: We really bonded a lot in those three weeks. 31 00:01:44,560 --> 00:01:47,000 LEALIA: I'm going to miss the class and the atmosphere. 32 00:01:47,000 --> 00:01:48,340 HANSOL: Everybody's talking to each other. 33 00:01:48,340 --> 00:01:49,970 And we're all getting to know each other. 34 00:01:49,970 --> 00:01:51,240 And we're all loud. 35 00:01:51,240 --> 00:01:54,440 ETHAN: The spirit of 5.301 will live on. 36 00:01:54,440 --> 00:01:56,320 NARRATOR: The chemistry department is getting a few 37 00:01:56,320 --> 00:01:58,210 more majors this year. 38 00:01:58,210 --> 00:02:00,620 DAN: Taking this lab class especially strengthened my 39 00:02:00,620 --> 00:02:01,970 desire to pursue chemistry. 40 00:02:01,970 --> 00:02:04,440 ANTHONY: I actually switched my major from chemical 41 00:02:04,440 --> 00:02:05,850 engineering to chemistry. 42 00:02:05,850 --> 00:02:07,480 I think it was the right choice for me. 43 00:02:07,480 --> 00:02:11,000 After 5.301, I realized that I really did like being in lab. 44 00:02:11,000 --> 00:02:14,940 I do have a strong passion for chemistry in that I could do 45 00:02:14,940 --> 00:02:16,520 it for the rest of my life. 46 00:02:16,520 --> 00:02:18,000 NARRATOR: Hansol doesn't know it yet. 47 00:02:18,000 --> 00:02:21,110 But she'll declare chemistry as well. 48 00:02:21,110 --> 00:02:23,840 At the end of the day, Dr. Dolhun meets with every 49 00:02:23,840 --> 00:02:26,650 student individually to say good bye and help 50 00:02:26,650 --> 00:02:28,640 them find a UROP lab. 51 00:02:28,640 --> 00:02:32,690 EMILY: He just wanted to say that he enjoyed having us and 52 00:02:32,690 --> 00:02:34,775 asked us what our plans were for our majors 53 00:02:34,775 --> 00:02:35,260 and stuff like that. 54 00:02:35,260 --> 00:02:37,660 ANTHONY: I just talked to him about how the class was, what 55 00:02:37,660 --> 00:02:38,500 I was thinking about doing. 56 00:02:38,500 --> 00:02:40,770 And he was letting me know that he'll be here to help us, 57 00:02:40,770 --> 00:02:43,690 read our drafts of emails to professors and stuff. 58 00:02:43,690 --> 00:02:47,920 NARRATOR: And just a few weeks later, Emily, Hansol, and Ike 59 00:02:47,920 --> 00:02:49,190 all have UROPs. 60 00:02:49,190 --> 00:02:52,520 EMILY: The research that I'm doing in the Essigmann lab is 61 00:02:52,520 --> 00:02:56,510 we are looking at some chlorouracil derivatives. 62 00:02:56,510 --> 00:02:59,510 And we're putting these lesions inside DNA. 63 00:02:59,510 --> 00:03:03,010 And we're testing it to see if it causes any mutations. 64 00:03:03,010 --> 00:03:06,550 And this can lead to diabetes and cancer. 65 00:03:06,550 --> 00:03:09,650 We're studying this just to locate exactly what each 66 00:03:09,650 --> 00:03:13,300 lesions do and how they affect the body. 67 00:03:13,300 --> 00:03:15,250 HANSOL: Hi, I'm in lab. 68 00:03:15,250 --> 00:03:18,820 The whole purpose of what I'm doing is to figure out how 69 00:03:18,820 --> 00:03:21,250 fast we can make peptide Fmoc chemistry. 70 00:03:21,250 --> 00:03:24,800 And right now, I'm currently designing an experiment to 71 00:03:24,800 --> 00:03:27,340 take a peptide at room temperature and compare it 72 00:03:27,340 --> 00:03:29,980 with how it couples under a microwave at 60 degrees, which 73 00:03:29,980 --> 00:03:31,970 is the optimal temperature. 74 00:03:31,970 --> 00:03:33,400 IKE: I got a UROP. 75 00:03:33,400 --> 00:03:36,035 Yeah, so they delivered on their promise. 76 00:03:36,035 --> 00:03:40,200 It's working with metal organic frameworks, or MOFs, 77 00:03:40,200 --> 00:03:45,010 which are really well structured organic molecules. 78 00:03:45,010 --> 00:03:46,390 The most important thing was 5.301. 79 00:03:46,390 --> 00:03:47,510 I took that. 80 00:03:47,510 --> 00:03:50,150 It was like, all right, this guy is prepared, you know? 81 00:03:50,150 --> 00:03:52,078 See ya. 82 00:03:52,078 --> 00:03:53,263 I'm out. 83 00:03:53,263 --> 00:03:55,530 I'm out. 84 00:03:55,530 --> 00:04:00,030 Monday, I wake up at 2:00 PM, yeah. 85 00:04:00,030 --> 00:04:02,300 NARRATOR: 5.301 was tough. 86 00:04:02,300 --> 00:04:04,760 But Anthony, Lina, Ike, Emily and the 87 00:04:04,760 --> 00:04:07,530 others met the challenge. 88 00:04:07,530 --> 00:04:10,760 IKE: Don't feel intimidated. 89 00:04:10,760 --> 00:04:11,820 You're still here, right? 90 00:04:11,820 --> 00:04:14,530 You still made it. 91 00:04:14,530 --> 00:04:17,709 Make the best of what you have. 92 00:04:17,709 --> 00:04:18,990 You're just like everyone else. 93 00:04:18,990 --> 00:04:20,190 You're as smart as everyone else. 94 00:04:20,190 --> 00:04:21,300 That's why you're here. 95 00:04:21,300 --> 00:04:22,240 You're here for a purpose. 96 00:04:22,240 --> 00:04:28,330 So do your thing, study hard, and you'll pass. 97 00:04:28,330 --> 00:04:29,480 I won't guarantee an A though. 98 00:04:29,480 --> 00:04:30,730 But you'll pass. 99 00:05:02,020 --> 00:05:03,520 PHIL: Oh no, don't film this.